diff --git a/CHANGELOG.md b/CHANGELOG.md
index 7df0348fb..d2b02b840 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -74,6 +74,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - #3865 - Added a new nightly icon and app name
 
 ### Changed
+- #3424 - Make talkback ignore ImageButton in Collection Selection by removing contentDescription and setting importantForAccessibility=no
 - #3278 - Updates strings in preferences
 - #2673 - Fixed can't upload files using third party apps from the file manager.
 - #1429 - Updated site permissions ui for MVP
diff --git a/app/src/main/java/org/mozilla/fenix/collections/CollectionCreationUIView.kt b/app/src/main/java/org/mozilla/fenix/collections/CollectionCreationUIView.kt
index 42704fb32..8fec68be0 100644
--- a/app/src/main/java/org/mozilla/fenix/collections/CollectionCreationUIView.kt
+++ b/app/src/main/java/org/mozilla/fenix/collections/CollectionCreationUIView.kt
@@ -144,7 +144,9 @@ class CollectionCreationUIView(
                 val drawable = view.context.getDrawable(R.drawable.ic_close)
                 drawable?.setTint(ContextCompat.getColor(view.context, R.color.photonWhite))
                 view.bottom_bar_icon_button.setImageDrawable(drawable)
-
+                view.bottom_bar_icon_button.contentDescription =
+                    view.context.getString(R.string.create_collection_close)
+                view.bottom_bar_icon_button.importantForAccessibility = View.IMPORTANT_FOR_ACCESSIBILITY_YES
                 view.bottom_bar_icon_button.setOnClickListener {
                     actionEmitter.onNext(CollectionCreationAction.Close)
                 }
@@ -203,10 +205,8 @@ class CollectionCreationUIView(
                 val drawable = view.context.getDrawable(R.drawable.ic_new)
                 drawable?.setTint(ContextCompat.getColor(view.context, R.color.photonWhite))
                 view.bottom_bar_icon_button.setImageDrawable(drawable)
-                view.bottom_bar_icon_button.setOnClickListener {
-                    actionEmitter.onNext(CollectionCreationAction.AddNewCollection)
-                }
-
+                view.bottom_bar_icon_button.contentDescription = null
+                view.bottom_bar_icon_button.importantForAccessibility = View.IMPORTANT_FOR_ACCESSIBILITY_NO
                 view.bottom_button_bar_layout.isClickable = true
                 view.bottom_button_bar_layout.setOnClickListener {
                     actionEmitter.onNext(CollectionCreationAction.AddNewCollection)
diff --git a/app/src/main/res/layout/component_collection_creation_select_collection.xml b/app/src/main/res/layout/component_collection_creation_select_collection.xml
index ceef3ae8d..cf38431e9 100644
--- a/app/src/main/res/layout/component_collection_creation_select_collection.xml
+++ b/app/src/main/res/layout/component_collection_creation_select_collection.xml
@@ -121,9 +121,9 @@
             android:layout_height="wrap_content"
             android:layout_margin="16dp"
             android:background="?android:attr/selectableItemBackground"
-            android:contentDescription="@string/create_collection_close"
             android:src="@drawable/ic_new"
             android:tint="?neutral"
+            android:importantForAccessibility="no"
             app:layout_constraintBottom_toBottomOf="parent"
             app:layout_constraintStart_toStartOf="parent"
             app:layout_constraintTop_toTopOf="parent" />